At the core of the SimCell System is the MicroBioreactor Array (MBA). The MBA leverages advanced microfluidics, gas-permeable membrane and optical measurement technologies to produce data that is predictive of process performance at manufacturing scale.
Each MBA consists of six miniaturized, independent MicroBioreactor chambers in one multiplexed, single-use array. The culture conditions inside each chamber can be independently defined, monitored and controlled for multiple process variables to meet a wide range of experiment designs. Optimized for mammalian cell culture, MBAs can perform standard batch and fed-batch production modes to execute experiments ranging from simple screening to full factorial experiment design.
Powerful cell culture benefits
A true breakthrough in cell culture technology, the MBA offers the power to:
- Simultaneously perform hundreds of cell cultures per month, faster and with fewer lab resources
- Meet the needs of a broad range of cell culture applications
- Optimize processes with in-process feedback and control during cell culture experiment
- Rapidly produce data that predicts cell culture performance in manufacturing-scale bioreactors
- 6 independent cell cultures per SimCell MBA
- Low media requirement-just 700µL
- Proprietary gas-permeable membranes eliminate the need for spargers or stirrers
- Microfluidic ports and channels allow aseptic automated inoculation, feeds, base addition, and sampling
Experience the power
To fully understand the SimCell advantage, you have to see it in action-and see the predictive data it produces. Request a SimCell Demonstration today.